Overweight and Obesity in Saudi Adults with Type 1 Diabetes Mellitus: (ADO)- Lupine Publishers

Overweight and Obesity in Saudi Adults with Type 1 Diabetes Mellitus by Khalid S Aljabri in  Archives of Diabetes & Obesity in Lupine Publishers

Background: Worldwide epidemic exists with respect to diabetes mellitus, primarily because of increased rates of obesity. The trend of increasing obesity prevalence has increased at a faster rate in patients with T1DM compared to the general population.

Methods: This cross-sectional study was conducted at Primary Health Care Clinics and the diabetes centre at King Fahad ArmedForces Hospital. A total of 237 Saudi with T1DM and 238 non diabtic patients (control) were randomly selected.

Result: A total of 475 patients attending the Primary Health Care Clinics and the diabetes centre were included in this study;193 (40.6%) were male, 282 (59.4%) were female with mean age 27.6±2.9 years. T1DM group comprised of 237 (49.9%) patients and non-diabetic (control) group comprised of 238 (50.1% ) of the sample. T1DM patients were not significantly different in age, had significant higher BM and HbA1c values when compared to control subjects. A comparison between both diabetic and control groups in relation to BMI subgroups and in relation to gender revealed that T1DM with BMI ≥ 30 (138(56.6%)) were significantly more frequent than control cases (106(43.3%)), P=0.003. However, Overweight and obesity were more frequent in female patients, there were no significant difference between gender. Obesity was significantly more frequent in female T1DM compared to control cases (76.1% vs 23.9%) with female to male ratio 3.2:1.0, p=0.03.

Conclusion: Patients with T1DM develop overweight and obesity more frequently than the general population. Gender-related differences in body weight in young type 1 diabetic adults were observed. The study stress that T1DM patients require special attention. This can be done through health education at the primary care level and the diabetic clinics.

https://lupinepublishers.com/diabetes-obesity-journal/abstracts/overweight-and-obesity-in-saudi-adults-with-type-1-diabetes-mellitus.ID.000115.php

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Epidemiology of Osteoporosis in Patients with Type 1 Diabetes Mellitus: (ADO)- Lupine Publishers

Epidemiology of Osteoporosis in Patients with Type 1 Diabetes Mellitus by Khalid S Aljabri in Archives of Diabetes & Obesity in Lupine Publishers

Background and Objective: The incidence of type 1 diabetes is increasing. Osteoporosis has become an alarming health problem throughout the entire world. The aim of this study were to estimate the epidemiology of osteoporosisamong Saudi patients with T1DM, living in the western province, attending the diabetes centre at King Fahd Armed Forces Hospital, Jeddah, KSA.

Methods: Eligible patients were older than 12 years old, had T1DM . All patients were recruited from the population of the Diabetic Centre at King Fahad Armed Forces Hospital. Eligible patients met with investigators for a complete history and physical examination, to have baseline laboratory assessments including glycosylated haemoglobin (HbA1c). HbA1c was expressed as percentage and measured using the high-performance liquid chromatography. BMD in the current study was measured using The Lunar Achilles (In Sight, GE Healthcare, USA), which is a proven bone ultrasonometer to avoid exposing the children to unnecessarily ionizing radiation. All measurements were converted to Z-scores using a data bank for age-matched speed of sound values supplied by the manufacturer. We excluded patients with a history of fractures of less than 1 year and those with associated bone/joint problems, liver disease or patients on long-term steroid therapy

Main results: 137 patients completed the study. There were 60 (44%) male and 77 (56%) were female with mean age 19.1±4.9. Osteoporosis was found in 53 of cases (38.7%) of patients. There were 23 (43.4%) male and 30 (56.6%) were female giving a female to male ratio 1.3:1. Osteoporosis was found in 53 of cases (38.7%) of patients. Baseline characteristics are shown in Table 1. Patients with osteoporosis were significantly younger, longer diabetes duration and have higher HbA1c than patients without osteoporosis. Osteoporosis was higher in females than male and was seen more in cases with HbA1c > 9.0 as compared to HbA1c groups of < 8.0 and 8-9, (Figures 1 & 2). Cases with longer diabetes duration (≥6years) have nonsignificant more frequent osteoporosis than cases with diabetes duration < 6 years, 34% vs. 66% respectively, p=0.4. There were no significant differences between genders and frequency of osteoporosis in relation to diabetes duration.

Conclusion: Our findings demonstrate lower BMD in young women with type 1 diabetes. Although bone density testing is not routinely performed in young women, these data suggest that screening may be important in young women with type 1 diabetes. In addition, these women should be counseled regarding lifestyle interventions that may improve bone health, including adequate intake of calcium and vitamin D, and exercise.

https://www.lupinepublishers.com/diabetes-obesity-journal/abstracts/epidemiology-of-osteoporosis-in-patients-with-type-1-diabetes-mellitus.ID.000114.php

https://www.lupinepublishers.com/diabetes-obesity-journal/fulltext/epidemiology-of-osteoporosis-in-patients-with-type-1-diabetes-mellitus.ID.000114.php

https://www.lupinepublishers.com/diabetes-obesity-journal/pdf/ADO.MS.ID.000114.pdf

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Oleuropein as a novel anti-diabetic nutraceutical. An overview: (ADO)- Lupine Publishers

Oleuropein as a novel anti-diabetic nutraceutical. An overview by Archives of Diabetes & Obesity in Lupine Publishers

Among the cardiometabolic diseases, type 2 diabetes mellitus (T2DM) is one of the most diffused worldwide. Pharmacological treatments commonly used present several side effects, and this is driving people to search natural approaches. Olea europaea is currently investigated for its anti-diabetic potential. In particular, oleuropein (OLE), its main bioactive compound, have been demonstrated to exert interesting activities in management of T2DM, including hypoglycemic and antioxidant activities. The purpose of this manuscript is to review the available scientific evidence evaluating the role of OLE in managing T2DM.

https://www.lupinepublishers.com/diabetes-obesity-journal/abstracts/oleuropein-as-a-novel-anti-diabetic-nutraceutical-an-overview.ID.000113.php

https://www.lupinepublishers.com/diabetes-obesity-journal/fulltext/oleuropein-as-a-novel-anti-diabetic-nutraceutical-an-overview.ID.000113.php

https://www.lupinepublishers.com/diabetes-obesity-journal/pdf/ADO.MS.ID.000113.pdf

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